In the context of vaccines manufactured to prevent COVID-19 pandemic, consider the following stateme

Question

In the context of vaccines manufactured to prevent COVID-19 pandemic, consider the following statements:The Serum Institute of India produced COVID-19 vaccine named Covishield using mRNA platform.Sputnik V vaccine is manufactured using vector based platform.COVAXIN is an inactivated pathogen based vaccine.Which of the statements given above are correct?

Accepted Answer

Covishield and Covaxin were the first vaccines permitted to be administered to people in India in the first half of 2021. Sputnik came weeks later.Covishield: It is not an mRNA-based vaccine. Covishield (produced by Serum Institute of India) is a recombinant, replication-deficient chimpanzee adenovirus vector encoding the SARS-CoV-2 Spike (S) glycoprotein. Following administration, the genetic material of part of coronavirus is expressed which stimulates an immune response. Hence statement 1 is not correct. By using elimination technique, one can reach option (b). Hence option (b) is the correct answer.Covaxin: It is an indigenous, inactivated pathogen type vaccine developed and manufactured in Bharat Biotech's BSL-3 (Bio-Safety Level 3) high containment facility. The vaccine is developed using Whole-Virion Inactivated Vero Cell derived platform technology. Hence statement 3 is correct.Sputnik V: It is an adenovirus viral vector vaccine for COVID-19 developed by the Gamaleya Research Institute of Epidemiology and Microbiology in Russia. It is the world's first registered combination vector vaccine for the prevention of COVID-19, having been registered on 11 August 2020 by the Russian Ministry of Health. Hence statement 2 is correct.